Mr. Lewis Gruber, Chairman, CEO and a founder of Arryx, Inc., was a founder of Hyseq, Inc. a publicly held biotechnology company, and was its CEO from 1994 through May 2000. While CEO of Hyseq, he raised over $70 million in a series of offerings, including the largest initial public offering of a biotechnology company in 1997 (underwritten by Lehman Bros., Salomon Smith Barney and Fahnestock & Co. Inc.). He also negotiated collaborations for Hyseq totaling over $102 million, including a $60 million collaboration with American Cyanamid Company in December 1999. Mr. Gruber is a member of the boards of iBIO (the Illinois chapter of the Biotechnology Industry Organization), AtomWorks (the Illinois Nanotech Industry Association), and of the advisory boards of the Center for
Biotechnology at Northwestern University's Kellogg Graduate School of Management, the Chicago and Argonne ITECs and the Illinois Medical District.

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